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A few more well-studied factors stand out

How Semaglutide and Tirzepatide Work for Weight Loss Semaglutide activates GLP-1 receptors in the brain and pancreas, slowing gastric emptying and increasing feelings of fullness after smaller meals

5 Medications that inhibit DPP-4 work by slowing the degradation of incretins, subsequently sustaining GLP-1 and GIP activity

Thomsen M, Dencker D, Wrtwein G, Weikop P, Egecioglu E, Jerlhag E, Fink-Jensen A, Molander A (2017) The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice

Contact your GP if taste changes cause persistent vomiting, dehydration, excessive weight loss, severe abdominal pain, or significantly impact nutritional status or quality of life