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Second, we did not account for some residual confounding even after adjusting potential confounders in our analyses

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FDA approves first oral GLP-1 treatment for type 2 diabetes. September 20, 2019

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Know that the insulin component creates hypoglycemia risk while the GLP-1 component causes gastrointestinal effects

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It is important to note that these data were obtained using a surrogate molecule and may not be directly extrapolated to the clinical candidate, Maridebart Cafraglutide (MariTide)

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More serious but rare side effects include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Changes in heart rate While these serious complications are uncommon, they underscore why these drugs require medical supervision

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The addition of tirzepatide to insulin glargine was evaluated in the SURPASS-5 study, focusing on patients with T2DM who had inadequate glycemic control

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