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176,210,211 These effects involve interactions with other satiety and hunger signals, such as PYY, CCK, insulin, and leptin
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Background: How GLP-1s evolved from diabetes treatment to anti-obesity medications Glucagon-like peptide-1 receptor agonists (GLP-1s) have a notable history in medical treatment, beginning as therapies for type 2 diabetes and later emerging as highly effective agents for weight loss
Participants received an injection of either semaglutide or a placebo once a week for 26 weeks
