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Hold the pen with the needle pointing down at a 90-degree angle to the skin

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The chronic relapsing nature of severe obesity and its comorbid diseases suggests the value of a staged minimally invasive (SMI) treatment approach that anticipates the necessity of long-term obesity management

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Compared with semaglutide QW, the discontinuation rate was significantly higher for dulaglutide (hazard ratio [HR] 1.22
