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57 Budak et al 58 found that exenatide increased the antioxidant capacity of human monocytes/macrophages in vitro, reducing oxidative stress by decreasing the expression of ROS-producing NADPH oxidase, increasing the expression and activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and decreasing ROS and malondialdehyde (MDA) levels

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To address these gaps, an advanced microsimulation model incorporating nationally representative data was used to provide more accurate clinical and economic estimates

3.4 Tirzepatide vs semaglutide 3.4.1 Study characteristics This section undertook a comprehensive examination of two RCT studies