when was glp-1 discovered JCI How GLP-1 Drugs Went From
Description
Native human GLP-1 has a very short half-life of approximately 2 minutes due to rapid degradation primarily by the enzyme dipeptidyl peptidase-4 (DPP-4), with neutral endopeptidase (NEP) also contributing to its breakdown
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Weight loss and achievement of minimal disease activity in patients with psoriatic arthritis starting treatment with tumour necrosis factor blockers
131,132,133 Additionally, GLP-1 helps to delay gastric emptying and suppress appetite, aiding in weight management
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doi: 10.1007/s11892-018-1011-7 61 VitaleMHaxhiJCirritoTPuglieseG
