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[1] [2] The severity varies considerably between individuals and is generally dose-dependenthigher doses tend to produce more pronounced gastrointestinal effects

[DOI] [PubMed] [Google Scholar] 198.Smith H.J., Sharma A., Mair W.B

doi: 10.1056/NEJMoa2107519 [DOI] [PubMed] [Google Scholar] 192.Ludvik B, Giorgino F, Jdar E, et al

What Is a Bowel Obstruction

By increasing the time it takes for food to leave the body, it also slows digestion
Meta-analyses across multiple trials confirm consistent efficacy, with pooled estimates showing mean weight reduction of 14.33% compared to placebo, accompanied by significant reductions in body mass index and waist circumference
