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Pharmacodynamic study in DIO mice Female DIO mice with a body weight approximately 22 g received tail vein injections of either saline (Saline), scExe4 donor plasmid loaded LNP only (Donor), or scExe4 donor plasmid loaded LNP plus Cas9 plasmid loaded LNP (Donor+Cas9)

The Digital Layer: Continuous Monitoring Changes What We Measure One dimension that transforms the Context of Use discussion is continuous digital phenotyping in preclinical research

Diabetes and obesity scientists have been using two main GLP-1 research approaches: DPP-4 inhibition and GLP-1 analogs

For me, this has felt like giving my metabolism a soft place to land while my hormones do their midlife rollercoaster dance

GLP-1s make it easier to lose weight, so smaller workouts still move the needle

Could genetic testing help optimize my GLP-1 dosing around procedures