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It is estimated that clinical trials evaluating liver-related events in patients with MASLD and compensated or decompensated cirrhosis would require a minimum recruitment of 2,886 patients with at least four years of follow-up and 1,602 patients with at least two years of follow-up, respectively

Below is a detailed overview of the most compelling findings Saxenda (Liraglutide): Proven for Moderate Weight Loss Saxenda, one of the earliest GLP-1 agonists approved for obesity treatment, was evaluated in the SCALE Obesity and Prediabetes trial , which followed 3,713 participants over 56 weeks

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In June 2023, Merck announced the results of a Phase IIa clinical trial of efinopegdutide for the treatment of NASH

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Understanding these pharmacokinetic differences helps explain why some practitioners might view injectable and oral formulations differently when evaluating lactation safety