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Description

Given the promising results in pre-clinical models (even in the absence of T2D), a unique mechanism of action and multiple age-related reduced disease risks that have been reported with acarbose, support for clinical trials with acarbose focusing on aging-related outcomes and incorporating biological sex, age at treatment initiation, and T2D-dependence within the design is warranted.

This discovery could lead to a tool enabling medical providers to identify the most effective weight loss interventions based on a person's genetic makeup.

Incretinas

GLP-1 weight loss treatments can come with side effects

Potential neural mechanisms for effects of GLP-1RAs on nicotine reward are reviewed, and priorities for future clinical and translational studies are discussed