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SMI strategies consider briefer stepwise surgical and medical treatments that can be deployed serially and/or concomitantly

Mounjaro is designed for long-term use as part of an ongoing weight management programme, and treatment duration is determined by your prescriber based on your progress, tolerability, and health goals

These effects were observed with central, but not peripheral, administration of the agonist and antagonist, suggesting receptor expression on the luminal, CSF-facing side of the choroid plexus, which aligned with GLP-1R-mediated modulation of luminally-expressed transporters in excised choroid plexus

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