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Endocr Connect 10(7):R200R212

Month 1: Women : 1.5 mg once weekly Men : 1.8 mg once weekly Month 2: Women: 3 mg once weekly (compared to the standard 5 mg) Men : 3.6 mg once weekly (compared to the standard 5 mg) Month 3: Women : 4.5 mg once weekly (instead of the standard 7.5 mg) Men : 5.4 mg once weekly (instead of the standard 7.5 mg) Doses can be gradually increased while remaining below standard titration levels

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Adderall, Concerta, Ritalin, Vyvanse, Zenzedi, and others are medications used to treat ADHD or narcolepsy

Neurodegeneration in ALS might result from a complex interaction of glutamate excitotoxicity, generation of free radicals, cytoplasmic protein aggregates, SOD1 enzymes, combined with mitochondrial dysfunction, and disruption of axonal transport processes through the accumulation of neurofilament intracellular aggregates