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doi: 10.1016/S2213-8587(17)30013-X 22 ArodaVRRosenstockJTerauchiYAltuntasYLalicNMMorales VillegasECet al

Most are given by injection, but there is one pill option (Rybelsus)
Because safety is not established, the FDA states that effects on the breastfed infant are unknown, despite limited data suggesting these medications transfer poorly into breast milk., Note: Undetectable levels are reassuring, but they are not the same as proven safety

Another notable issue is the heterogeneity of metabolism, which could be crucial in treating MASLD

Additionally, Lilly saw no signs of liver-related safety issues

126 These studies suggest that GLP-1R could be a potential target for creating new treatments for cerebral ischemic stroke and human neurodegenerative disorders
