retatrutide and type 1 diabetes Diagram showing the mechanism of action of Retatrutide—A Game Changer in Obesity

Obesity is a growing epidemic in the U.S., and by 2030 nearly one in two adults will have obesity

GLP-1 diabetes and weight-loss drug side effects: Ozempic face and more

Gabe MBN, van der Velden WJC, Gadgaard S, et al

The cell wall acts as a natural enteric capsule, shielding the GLP-1 molecules from pepsin and the acid bath of the stomach, and releasing it progressively as it transitions into the higher-pH environment of the duodenum

This is one of the strongest arguments against starting keto and GLP-1 at the same time

[1] At the cellular level, GLP-1 and GIP receptor activation enhances insulin secretion and slows gastric emptying, contributing to reduced caloric intake and improved glycemic control