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85: 20992119 [DOI] [PubMed] [Google Scholar] 139.Kaplan AM, Vigna SR

For instance, Hanmi Pharmaceutical stated in September 2021 announced that its new, long-acting diabetes biologic drug, efpeglenatide (GLP-1 RA), was shown to significantly reduce incidences of major adverse cardiovascular events (MACE) and kidney disease

However, the effect was self-limiting, with the insulin-stimulating activity attenuated as plasma glucose levels started to fall, limiting the fall to 0.51 mmol/l

Now add GLP-1 medications to the picture

Despite robust efficacy and being the first once-weekly formulation to reach the market, sales of Bydureon fell short of expectation

Byetta (Exenatide): Whats it Approved For