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Tirzepatide is a promising drug withdual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor activation that has revolutionized the treatment of type 2 diabetesmellitus (T2DM) as an adjunct to ...

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The metabolic rate of GLP-1R KO mice was significantly slower than that of WT mice (p=0.0345, WT mice 0.023350.057mM/min, GLP-1R KO mice 0.019980.07mM/min)

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