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Crowe, L

[DOI] [PubMed] [Google Scholar] 42.Gallwitz B, Guzman J, Dotta F, et al

A large-scale genome-wide association study published in Nature in April 2026, conducted by 23andMe researchers using data from 27,885 GLP-1 medication users, identified a specific variant in the GLP1R gene the gene that encodes the primary receptor these drugs target associated with differential weight loss efficacy

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As a health coach, I've seen firsthand how hormonal changes during this time can impact metabolism and make weight management more difficult

However, given its limited availability and lack of head-to-head studies compared to ultrasound, the same guidelines do not recommend it as a first-line technique