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For a medicine to receive UK marketing authorisation, the manufacturer must submit a comprehensive dossier of evidence including Phase 3 clinical trial data demonstrating that the product meets the required standards of safety, efficacy, and quality

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Dalla scoperta che il tiazolidinedione rosiglitazone ha aumentato gli eventi cardiovascolari, stato attribuito un peso notevole sulla sicurezza dei nuovi farmaci ipoglicemizzanti