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For many women, both perimenopause and menopause feels like the moment their body suddenly starts playing by different rules
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Gastrointestinal (GI) adverse eventsparticularly nausea, vomiting, diarrhea, and constipationare the most common side effects, generally emerging during dose escalation and resolving over time

References: Abbass et al., AJO 2025

Emerging effects of DPP-4 on bone metabolism include an inverse relationship between DPP-4 activity levels and bone mineral density, along with an increased risk of fractures
