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Chemical modifications such as lipidation (first applied therapeutically to insulin in the 1990s), PEGylation (established as a platform technology in the early 2000s), and reversible albumin binding have transformed peptides from short-lived signaling molecules into durable therapeutics suitable for weekly or even monthly administration ( In parallel, advances in formulation science and delivery technologies have expanded the feasible routes of peptide administration

We cover the foundations of diagnosis and management that will be helpful to CardioNerds preparing to encounter hypertrophic cardiomyopathy on the boards or on the wards

What GLP-1 Does After You Eat After a meal, GLP-1 rises in your blood

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This has been an issue for higher numbers of American adults who are Black or Hispanic, according to a 2022 article in the Journal of the American Heart Association (JAHA) , on which Dr

The recently published FLOW trial, conducted on 3533 patients and followed up for 177 weeks, comparing injectable once weekly semaglutide with placebo, revealed that semaglutide reduced the risk of clinically important kidney outcomes and death from cardiovascular causes in patients with type 2 diabetes and chronic kidney disease [8]