glp 1 and hormones GLP-1: Another Hormone Making the Case for Paleo What is GLP-1 & Does
Description
North Carolinas Medicaid program dropped its coverage of the drugs this month, citing their high cost

Weight Loss Results Published clinical trial data for semaglutide shows average weight loss of 1517% of body weight over 68 weeks
Effects of Ketogenic Diet on Health Outcomes: An Umbrella Review of Meta-Analyses of Randomized Clinical Trials

Because GLP-1s are intended to be used alongside lifestyle changes, pairing medication with nutrition, behavior change, and metabolic health support may help employers maximize the value of these medications

NOT recommended for treatment of type 1 diabetes or treatment of diabetic ketoacidosis Pharmacokinetics: oral administration, 65% bioavailability activity is terminated by conversion to inactive O-glucuronide metabolites (that are eliminated in the urine), with only minimal (~7%) metabolism by CYP3A4

A: The evidence is mixed