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doi: 10.1210/endo.143.6.8840

Amino acid sequence and heterogeneity of gastric inhibitory polypeptide (GIP)

doi: 10.1038/s41598-017-09898-4

Reduced appetite is the intended effect, though it sometimes feels too extreme

Unlike standard GLP-1 compounds, Retatrutide activates three metabolic pathways instead of one, creating a broader physiological response

However, the hormone proved disappointing in initial trials
