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Lancet Diabetes Endocrinol (2021) 9(10):65362

48 MaksimovicS.NakataniM.BabaY.NelsonA

Clinical trials have demonstrated hemoglobin A1c reductions of 1.9% to 2.4% in type 2 diabetes (SURPASS trials), and weight loss of approximately 15% to 21% after 72 weeks in patients with obesity (SURMOUNT-1)

[1] [2] Marketed under the brand names Mounjaro (for diabetes) and Zepbound (for weight management), tirzepatide represents a significant advancement in metabolic disease therapy due to its dual incretin receptor activity

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