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Any potential additive effect could be attributable to differential mechanisms of action of the two classes of medication, and mechanistic interaction was suggested in an experimental study of diabetic mice in which finerenone prevented downregulation of GLP-1 receptors in the kidney (16,25)

Am J Physiol Endocrinol Metabol

Per a March 3, 2026 FDA press announcement (FDA.gov press announcement, March 3, 2026), the FDA issued warning letters to 30 telehealth companies for making false or misleading claims about compounded GLP-1 products, including claims implying sameness with FDA-approved medications

Association between GLP-1 RA and atrial arrhythmias GLP-1 RA therapy in patients with DM2 was not associated with increased risk of atrial arrhythmias (odds ratio 0.963, 95% confidence interval 0.8691.066

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