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however, differences are observed in hepatic VLDL production in female (but not male) rats after VSG 38

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Enhanced glucose-dependent insulin secretion: Glucose dependent stimulated insulin release from pancreatic -cells, which improves glycemic control

An alternate or additional form of contraception should be considered in patients prescribed concomitant therapy with enzyme-inducing anticonvulsants, or higher-dose hormonal regimens may be indicated where acceptable or applicable