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The role of inflammation in diabetes: current concepts and future perspectives

While surgery is an effective weight-loss solution, patients must commit to pre-specified weight-loss requirements to become suitable candidates

In STEP-4 (NCT03548987), maintenance semaglutide after 20 weeks for another 48 weeks led to a further 7.9% bodyweight loss for a total 17.4% weight loss over the whole trial, whereas those who switched to placebo regained an average 6.9% (total weight loss of 5.0%) [66]

Despite encouraging preclinical and early clinical evidence, several challenges remain

Ozempic (semaglutide) belongs to a class of medications known as glucagon-like peptide-1 receptor agonists (GLP-1 agonists)

Tralokinumab for moderate-to-severe UC: a randomised, double-blind, placebo-controlled, phase IIa study