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These studies highlight the importance of continued treatment for sustained success
Discordance between central (brain) and pancreatic action of exenatide in lean and obese subjects
All participants in the orforglipron treatment arms started the study at a dose of orforglipron 1 mg once-daily and then increased the dose in a step-wise approach at four-week intervals to their final randomised maintenance dose
Because it is not a peptide, orforglipron does not depend on absorption enhancers to survive the gut environment
doi: Bader S, Bhatti R, Mussa B, Abusanana S
