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ACS Appl Mater Interfaces 14(1):6993 Handy JA et al (2011) Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis
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Nausea is typically the most prominent symptom, particularly during dose escalation periods
Laboratory studies show it reduces macrophage production of several pro-inflammatory cytokines and increases IL-10 production