does medicare cover glp 1 meds GLP-1/GIP Tirzepatide Rx FDA says shortage of GLP-1

BURN30 GLP1+ is not a prescription GLP-1 medication and should not be treated like one

Although this class of drugs, called glucagon-like peptide-1 or GLP-1, have been around for more than 17 years, with the first one, Byetta, approved in 2005, it is only recently that the class has made a big name for itself with the introduction of the popular once-weekly diabetic drug, Ozempic , and the equally popular obesity drug, Wegovy (the same drug as Ozempic but with a different dose)

Cardiovascular death: 2.5% (Wegovy) vs 3.0% (placebo) Heart failure composite: 3.4% vs 4.1% All-cause death: 4.3% vs 5.2% A related study determined that 100 people with obesity would need to be treated for three years to prevent one major cardiovascular event

Facial deflation, a hallmark of GLP-1 therapy use, can age the appearance dramatically by hollowing the cheeks and under-eye areas

On mechanism, the peptides and the small molecules end up at the same destination (Gs activation, cAMP elevation, the canonical incretin pharmacology) but they get there via different binding modes and with different signalling profiles

Yi et al., 2024)