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[DOI] [PubMed] [Google Scholar] 108.Gerstein HC, et al

In the STEP trials, semaglutide produced average weight loss of 1518% at the 2.4 mg maintenance dose, with approximately 80% of participants achieving clinically significant (5%) weight loss

It took a lot of advancements in peptide chemistry and drug making to get to where we are today, with pretty convenient, long-acting, and now dual-acting versions of this pathway, the incretin

Tirzepatides dual receptor agonism may result in more weight loss and better glucose control than Ozempic which only activates the GLP-1 receptor

in: PubMed | Google Scholar | Authorship note: AFR and VM are cofirst authors

Adequate hydration represents an important intervention