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Glucagon-like peptide-1 receptor agonist (GLP-1RAs) and more recently Twin-Cretins (GLP+GIP) are frequently used for patients with diabetes and associated obesity

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Changes in the expression of GLP-1R, Iba-1, PI3K and p-Akt in the TNC were examined by western blotting

Moreover, to account for possible confounders, adjusted ORs (mainly based on age, sex, body mass index [BMI], diabetes) were pooled and analyzed

We have assessed various metabolic parameters after short and long exposure of clonal BRIN-BD11 -cells and rodent islets to the GLP-1R agonist Exendin-4 (50nM)