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The latter should not be used

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Thyroid Cancer: Tirzepatide may carry a theoretical risk for thyroid tumors, though this is based on animal studies and has not been confirmed in humans

Low protein consumption due to reduced appetite may also contribute to muscle loss and increased risk for sarcopenia, particularly among those with older age, perimenopausal or menopausal, lower testosterone, sedentary behavior, or lack of resistance/strength training [[63], [64], [65], [66]]

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