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In the STEP-HFpEF trial, treatment with 2.4 mg of the glucagon-like peptide-1 receptor agonist semaglutide weekly produced substantial improvements in symptoms, physical limitations and exercise function and reduced inflammation and resulted in greater weight loss compared to placebo 11,12

o Of importance o This study links circulating LEAP2 concentrations with improved pancreatic insulin secretion in adults living with overweight or obesity

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There are several clinical, laboratory, and radiologic risk factors and scoring systems that are used to predict severity of Acute Pancreatitis, but none is optimal