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In this Review, the authors discuss guideline-directed medical therapy for diabetic kidney disease and the evolving clinical evidence for next-generation therapies, including incretin-based therapies, endothelin receptor antagonists, aldosterone synthase inhibitors, soluble guanylate cyclase agonists and anti-inflammatory therapies.

GLP-1 is a product of pre-pro-glucagon gene expression in the L-cells of the intestinal mucosa

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that treat CVD, diabetes and obesity, Harold Edward Bays, MD, president-elect of the Obesity Medicine Association, told Healio.

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