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The authors connect this to something known as the rate hypothesis in addiction research: the faster a substance hits the brain, the stronger and more rewarding it feels

Here is what the REDEFINE data shows and what comes next

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Some sub-analyses of large clinical trials suggest that GLP-1RA and sodium-glucose cotransporter 2 inhibitor combination therapy may provide more significant reductions in heart failure hospitalization and renal composite events than each alone

To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease, affecting up to 70% of patients with diabetes