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Insulin/IGF-driven Cancer Cell-Stroma Crosstalk as a Novel Therapeutic Target in Pancreatic Cancer

In contrast, ferulic acids role in GLP-1 regulation remains less well understood, despite its presence in yerba mate and other plant-derived foods

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Both overeating and excessive drinking are mediated by the mesolimbic dopamine pathway the brains reward circuit

The apparent physiological opposition between GLP-1 and GCG does not preclude pharmacological synergy, since GLP-1/GCG dual agonists are engineered to achieve balanced receptor activation rather than simple co-administration of two counter-regulatory hormones (61,64)