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GLP-1 is a hormone produced in the gut that is releasedafter eating, and plays a key role in weight loss, glucosemetabolism, and appetite regulation

Main body Obesity may alter the synchronized working of the reproductive-endocrine milieu, mainly the hypothalamic-pituitary-gonadal (HPG) axis along with its crosstalks with other reproductive hormones

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They go through relatively small clinical trials, and then theyre released into the real world, where millions of people take them in ways they were never studied