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Wednesdays approval is supported by data from the Phase III ENHANCE-1 and ENHANCE-2 studies, where Ohtuvayre significantly improved lung function in COPD patients

These include new or worsening psychiatric symptoms such as hallucinations, delusional thinking, or manic episodes

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Both Wegovy and liraglutide resist this breakdown, so their effects last much longer

In fact, DPP-4 inhibitors prevent the degradation of GLP-1 and GIP and increase the insulin action after an oral glucose load (incretin action), thus increasing insulin release by the pancreatic cells, also acting on the cells to reduce glucagon release and hepatic glucose production [54]

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