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At the end of each 4-week period, your blood levels have reached a stable plateau at the current dose
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423 It was observed that the GLP-1RA, exendin-4, significantly reduced the TNF- levels caused by various TLR agonists, indicating that exendin-4 can lower the TNF- levels induced by multiple TLR agonists
Paulescu published his results the following year and then took out a Romanian patent on his technique in April 1922
