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This article explores the concept of dose splittingoften called microdosingthe science behind why people consider it, and the critical importance of medical supervision

Product Specifications and Features: The device is slim and discreet The pen has a magnification window with a clear dose Both sides have a dose arrow Bayonet cartridge lock helps securely lock the cartridge The dialling distance is short The pen allows reverse dialling without penalty The maximum dose dialling is 80 units An audible click sound is produced when every unit is dialled and dispensed The dial button does not rotate during dispensing Contents: 1 AllStar, one carry case, one instruction manual, and one warranty card Compatible With: 3ml (300 units) insulin cartridges (U-100) from Sanofi Group Directions for Use: Insert a new cartridge into the pen by pulling off the cap and unscrewing the cartridge holder from the body Insert the new cartridge into the holder, narrow end first Screw the cartridge holder onto the pen body until a click sound is heard Check your insulin before every injection and attach a new needle for each use Select the dose and inject the dose After use, remove the needle and discard it Safety Information: Contact a healthcare professional for information about proper injection technique before using the product Take special care not to touch the needle tip to avoid accidental needle injury and passing of infectious diseases Store AllStar in the carry case provided Do not store AllStar in the refrigerator between injections If the insulin cartridge has been attached to AllStar, follow the storage conditions indicated in the insulin leaflet Read the label carefully before use Keep away from the reach of children Store in a cool and dry place Quick Tips: Take a new cartridge out of the refrigerator at least 1 hour before you inject

The Linus Pauling Institute recommends the consumption of a diet high in potassium-rich foods (see Sources), especially fruit, vegetables, nuts, and dairy products to ensure adequate potassium intakes

Clin J Am Soc Nephrol CJASN 2015;10(7):11361144

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