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Although GLP-1RAs are widely used, data concerning their safety during pregnancy, particularly with respect to fetal development, remain limited.225 Some investigations have suggested that GLP-1RAs may indirectly influence pregnancy outcomes by ameliorating maternal metabolic status

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If vomiting persists for more than 2448 hours or you cannot keep fluids down, contact your GP urgently for advice on whether to temporarily pause treatment and how to manage your symptoms safely

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The incidence of both pancreatitis and pancreatic cancer is increased in individuals with obesity and/or type 2 diabetes (2123), although the underlying mechanisms are not well understood (Fig