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While an increased odds ratio (OR) was evident for bowel obstruction with GLP-1RAs (OR 3.05, 95% CI 2.54-3.66), reporting rates varied substantially from year to year (eg, odds ratios for GLP-1RAs varied between 1 in the years 2008, 2010, 2013, and 2014 vs 3 in 2009, 2011, 2012, and 2015)

To evaluate cognitive function, the Morris water maze and Barnes maze tests were used

The MHRA's Yellow Card scheme allows reporting of suspected side effects from both medicines and herbal products, contributing to ongoing safety monitoring

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Its expensive, often difficult to get due to shortages, and still relatively new, meaning its long-term effects arent as well understood

Barrett LF, Quigley KS, Hamilton P