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Understanding the implications of upstream GLP-1 signaling may provide context for metabolic disease states, where abnormalities in the TGR5 signaling pathway attenuate robust GLP-1 activity

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SS-31 is a cell-permeable peptide that concentrates on the inner mitochondrial membrane, where it stabilizes cardiolipin and protects the electron transport chain from oxidative damage

When that foundation is shaky, everything else, the heart, the kidneys, the liver, the brain, suffers

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