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News outlets have reported that the companys response has been unperturbed, dismissing concerns about possible vision loss after taking Ozempic and reiterating that the data is insufficient to show a strong connection between semaglutide and NAION

Phase 2 data showed 24.2% weight loss at 48 weeks with the same dose

Excitement has grown in this drug class, with several GLP-1R agonists demonstrating benefit in cardiovascular outcomes studies ( 10 )

Disclaimer: While Semaglutide has shown strong results in clinical trials, individual outcomes can vary

doi: 10.1002/osp4.124

Less expression is also described in other tissues such as the heart, pancreas, adipose tissue, and the GI tract