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Here, the authors report cryo-EM structures of tirzepatide-bound GIPR and GLP-1R, peptide 20-bound GIPR, GLP-1R and GCGR, revealing the molecular basis of their multiplexed pharmacological actions.

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A therapy that transformed adult diabetes care is now extending its impact to younger patients, helping prevent complications before they begin

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Heres your first-month guide - what to expect, common side effects, and tips to ease the transition.
