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Section 2: Evidence from human clinical studies on the effects of GLP-1 RAs in modulating IBD outcomes

Incretin-based therapies: focus on effects beyond glycemic control alone

Furthermore, the EMA has withdrawn the weight loss medication rimonabant, a selective cannabinoid type 1 receptor antagonist, due to its reported links to increased risks of depression and suicide [70]

Increased gene expression of connective tissue growth factor (CTGF), a profibrotic cytokine in DKD rats was reduced by EMPA + LINA

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