where does glp 1 drug come from Study finds GLP-1 receptor agonists target fat over muscle for weight loss GLP-1s Continue to Reshape How
Description
While NNC00902746 was generated by chemical modification of a glucagon/GLP-1 co-agonist, tirzepatide was developed by selective alterations in the native GIP sequence to provide agonism at the GLP-1R 44

The cost of these medications often depends on the dosage we prescribe, the duration of treatment, your insurance coverage, and the pharmacy you choose

doi: 10.1001/jamaoto.2024.4852, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 175

Clinical trial description

Company announcement, 24 November 2025

This modification extends its half-life, making it suitable for a once-weekly subcutaneous injection formulation [85,86]
