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doi: 10.3389/fimmu.2019.01223

The trial also assessed clinically meaningful thresholds: over 90% of participants on 4 mg or higher doses lost at least 5% of body weight, and 6083% of them reached 15% or greater reduction, compared with just 27% and 2%, respectively, in the placebo group

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The focus is on key considerations for clinicians when selecting these medications, including long-term safety, efficacy, potential adverse effects, and overall clinical utility

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Nodules : Large, painful lumps beneath the skin, caused by severe inflammation
