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Ove fluktuacije eera u krvi gotovo uvek dovode do udnje za hranom (najvie slatkiima i drugom ultra-procesuiranom hranom), kao i do usvajanja nepravilnih i nezdravih prehrambenih navika u ishrani

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Giachelli C.M., Lombardi D., Johnson R.J., Murry C.E., Almeida M

Glucagon enhances multiple steps in this pathway: Increased lipolysis: Glucagon activates hormone-sensitive lipase in adipose tissue, releasing more fatty acids into circulation Reduced lipogenesis: Glucagon suppresses the enzymes responsible for creating new fat from carbohydrates Enhanced hepatic oxidation: Glucagon upregulates liver enzymes involved in fatty acid oxidation Ketogenesis: When fat oxidation exceeds the citric acid cycle capacity, excess acetyl-CoA is converted to ketone bodies, an alternative fuel source The net effect is a metabolic state favoring fat breakdown over fat storage

In studies treated with cabergoline, reduction in fasting insulin and HOMA-IR also correlated with cabergoline dose but not to body weight and BMI, suggesting that directly cabergoline could modulate insulin secretion and sensitivity