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Description
Brown adipose tissue and thermogenesis
Phentermine's sympathomimetic stimulation combined with semaglutide's direct cardiovascular effects creates compounded stress on the heart, particularly in people with existing hypertension or arrhythmia history
Furthermore, a GLP-2 analogue with a single amino acid substitution [Gly2]-GLP-2 exhibited substantial resistance to DPP-4 cleavage and robust intestinotrophic activity in normal rats in vivo (60)
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TA875: Semaglutide for managing overweight and obesity
10.1056/NEJMoa2206038 61 JellingerK
